The CARE guideline for writing a case report or case series.

About this guideline

This guideline is relevant to case reports and case series,

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Reporting guidelines are best used early:

  • Use a template to write quickly and avoid the blank page
  • Use a checklist to double-check and reassure others that your work is described transparently

For drafting

For checking

For planning

Guidance

Approx. 1 min read

Title

1. Title

The area of focus and “case report” should appear in the title

Keywords

2. Keywords

Two to five key words that identify topics in this case report

Abstract

3a. Introduction

What is unique and why is it important?

3b. Abstract

The patient’s main concerns and important clinical findings.

3c. Abstract

The main diagnoses, interventions, and outcomes.

3d. Conclusion

What are one or more “take-away” lessons?

Introduction

4. Introduction

Briefly summarize why this case is unique with medical literature references.

Patient information

5a. Patient information

De-identified demographic and other patient information.

5b. Patient information

Main concerns and symptoms of the patient.

5c. Patient information

Medical, family, and psychosocial history including genetic information.

5d. Patient information

Relevant past interventions and their outcomes.

Clinical findings

6. Clinical findings

Relevant physical examination (PE) and other clinical findings.

Timeline

7. Timeline

Relevant data from this episode of care organized as a timeline (figure or table).

Diagnostic assessment

8a. Diagnostic assessment

Diagnostic methods (PE, laboratory testing, imaging, surveys).

8b. Diagnostic assessment

Diagnostic challenges.

8c. Diagnostic assessment

Diagnostic reasoning including differential diagnosis

8d. Diagnostic assessment

Prognostic characteristics when applicable

Therapeutic Intervention

9a. Therapeutic Intervention

Types of intervention (pharmacologic, surgical, preventive).

9b. Therapeutic Intervention

Administration of intervention (dosage, strength, duration)

9c. Therapeutic Intervention

Changes in the interventions with explanations.

Follow up and outcomes

10a. Follow up and outcomes

Clinician and patient-assessed outcomes when appropriate

10b. Follow up and outcomes

Important follow-up diagnostic and other test results.

10c. Follow up and outcomes

Intervention adherence and tolerability (how was this assessed)?

10d. Follow up and outcomes

Adverse and unanticipated events.

Discussion

11a. Discussion

Strengths and limitations in your approach to this case.

11b. Discussion

Discussion of the relevant medical literature.

11c. Discussion

The rationale for your conclusions.

11d. Discussion

The primary “take-away” lessons from this case report.

Patient perspective

12. Patient perspective

The patient can share their perspective on their case